US company LyGenesis is about to begin clinical trials in which participants are expected to develop “ectopic” livers (livers that grow outside of the body in response to injected donor cells).

Nanoparticle Probiotic “Backpacks” Show Promise for Treating Inflammatory Bowel Diseases Like Crohn’s and Ulcerative Colitis

Researchers at the University of Wisconsin–Madison have designed specialized nanoparticles to neutralize molecules implicated in IBD. They’ve also figured out a way of attaching these nanoparticle “backpacks” to beneficial bacteria after encasing them in the protective coating. 

Stanford Medicine Scientists Sequence Patient’s Whole Genome in Just Five Hours Using Nanopore Genome Sequencing, AI, and Cloud Computing

In as little as five hours, Stanford University School of Medicine has developed a method for rapid sequencing of patients’ whole human genome. The researchers used their breakthrough to diagnose rare genetic diseases in under eight hours, according to a Stanford Medicine news release.

Scientists Use CRISPR for Personalized Cancer Treatment

A small clinical trial has shown that researchers can use CRISPR gene editing to alter immune cells so that they will recognize mutated proteins specific to a person’s tumors.

AI transforms smartwatch ECG signals into a diagnostic tool for heart failure

A study published in Nature Medicine reports the ability of a smartwatch ECG to accurately detect heart failure in nonclinical environments. Researchers at Mayo Clinic applied artificial intelligence (AI) to Apple Watch ECG recordings to identify patients with a weak heart pump. 

NMN De-Ages the Brain by Improving Neurovascular Coupling

A group of researchers has demonstrated that treatment with NMN, a precursor of NAD+, restores neurovascular coupling (NVC) in aged mice.

Exscientia and MD Anderson partner to use AI for cancer therapy

Exscientia and The University of Texas MD Anderson Cancer Center have entered a strategic partnership to use artificial intelligence (AI) to develop new cancer therapies.

New Compound Clears Arterial Plaque to Reverse Heart Disease

Cyclarity Therapeutics is developing technology to treat, cure and reverse atherosclerosis. The company’s tech uses rationally-designed cyclodextrin molecules that remove arterial plaque by clearing the non-degradable oxidised cholesterol that accumulates within cells in the arterial walls.

MIT Scientists Develop a New CRISPR Control System for Synthetic Genes

MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells using an approach based on CRISPR proteins.

Evidence mounts for spermidine’s potential in reversing aging

Clinical studies are exploring spermidine’s potential in the treatment and prevention of chronic disease, including cardiovascular disease and obesity. A recent study found that dietary spermidine intake showed statistically significant correlations with cardiovascular disease mortality and all-cause mortality.

Patient Cancer Free After Cell Therapy Created by CU Anschutz

A new clinical trial at the University of Colorado Anschutz Medical Campus is using cells genetically engineered by medical faculty to fight stubborn cancers. The chimeric antigen receptor T cells, or CAR-T cells, are being infused into patients with difficult to treat or frequently recurring cancers at UCHealth University of Colorado Hospital.