Scientists at the University of Cologne have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA). Using a mouse model in which mtDNA mutations lead to impaired muscle regeneration, the scientists were able to demonstrate that selectively mutated mtDNA can be removed by stimulating the activity of the autophagy mechanism with rapamycin.

New AI blood testing technology detects more than 80% of liver cancers

DELFI, a novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers, has successfully detected lung cancer in a 2021 study and more than 80% of liver cancers in a new study of 724 people.

These Engineered Cells Are Super Soldiers That Hunt Down Cancers

CRISPR and CAR-T are being combined in order to create a more targeted cancer therapy that is less harsh on the body. The new therapy is personalized to each patient’s individual cancer.

Scientists Discover a Gene That Could Prevent Alzheimer’s Disease

Researchers at the University of Colorado Anschutz Medical Campus find that overexpression of a gene linked to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer’s disease (AD), despite the presence of amyloid beta (Abeta).

New CRISPR-based tool “PASTE” can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

New CAR-T Cell Therapy Reverses Auto-Immune Disease

CAR T cells have shown promise in fighting blood cancers, and now there is evidence that they may also be effective in treating autoimmune diseases such as lupus. In a small study, all patients went into remission after receiving CAR T therapy and were able to stop taking their lupus drugs within three months.