{"id":10071,"date":"2022-11-25T13:38:00","date_gmt":"2022-11-25T21:38:00","guid":{"rendered":"https:\/\/kyla.com\/p\/?p=10071"},"modified":"2023-03-23T16:11:51","modified_gmt":"2023-03-23T23:11:51","slug":"longevity-in-the-news-discovery-of-new-mitochondrial-cleanup-mechanism-paves-way-for-longevity-therapies","status":"publish","type":"post","link":"https:\/\/kyla.com\/p\/blog\/longevity-in-the-news-discovery-of-new-mitochondrial-cleanup-mechanism-paves-way-for-longevity-therapies\/","title":{"rendered":"Longevity in the News: Discovery of New Mitochondrial Cleanup Mechanism Paves Way for Longevity Therapies"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"683\" src=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05151906\/mitochondria-waste-disposal-1024x683.jpg\" alt=\"\" class=\"wp-image-10090\" srcset=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05151906\/mitochondria-waste-disposal-1024x683.jpg 1024w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05151906\/mitochondria-waste-disposal-300x200.jpg 300w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05151906\/mitochondria-waste-disposal-768x512.jpg 768w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05151906\/mitochondria-waste-disposal-1536x1024.jpg 1536w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05151906\/mitochondria-waste-disposal-2048x1366.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong>Research team identifies how cells\u2019 powerhouses get rid of mutated mtDNA, identifying a new molecular target that could lead to treatment for age-associated diseases.<\/strong><\/figcaption><\/figure>\n\n\n\n<p><a href=\"https:\/\/longevity.technology\/news\/discovery-of-mitochondrial-waste-disposal-mechanism-could-open-up-new-therapeutic-options\/\">Scientists at the University of Cologne<\/a> have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA). Using a mouse model in which mtDNA mutations lead to impaired muscle regeneration, the scientists were able to demonstrate that selectively mutated mtDNA can be removed by stimulating the activity of the autophagy mechanism with rapamycin.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"585\" src=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152448\/blood-test-1024x585.jpg\" alt=\"\" class=\"wp-image-10094\" srcset=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152448\/blood-test-1024x585.jpg 1024w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152448\/blood-test-300x171.jpg 300w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152448\/blood-test-768x439.jpg 768w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152448\/blood-test-1536x878.jpg 1536w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152448\/blood-test-2048x1170.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h1><a href=\"https:\/\/www.news-medical.net\/news\/20221120\/New-AI-blood-testing-technology-detects-more-than-8025-of-liver-cancers.aspx\">New AI blood testing technology detects more than 80% of liver cancers<\/a><\/h1>\n\n\n\n<p>DELFI, a novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers, has successfully detected lung cancer in a 2021 study and more than 80% of liver cancers in a new study of 724 people.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"576\" src=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152228\/t-cell-immune-system-electron-micrograph-image-1024x576.jpeg\" alt=\"\" class=\"wp-image-10092\" srcset=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152228\/t-cell-immune-system-electron-micrograph-image-1024x576.jpeg 1024w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152228\/t-cell-immune-system-electron-micrograph-image-300x169.jpeg 300w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152228\/t-cell-immune-system-electron-micrograph-image-768x432.jpeg 768w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152228\/t-cell-immune-system-electron-micrograph-image.jpeg 1068w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h1><a href=\"https:\/\/singularityhub.com\/2022\/11\/21\/these-engineered-cells-are-super-soldiers-that-hunt-down-cancers\/\">These Engineered Cells Are Super Soldiers That Hunt Down Cancers<\/a><\/h1>\n\n\n\n<p>CRISPR and CAR-T are being combined in order to create a more targeted cancer therapy that is less harsh on the body. The new therapy is personalized to each patient&#8217;s individual cancer.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"777\" height=\"437\" src=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152617\/DNA-Genetics.gif\" alt=\"\" class=\"wp-image-10095\"\/><figcaption class=\"wp-element-caption\"><strong>Research team identifies how cells\u2019 powerhouses get rid of mutated mtDNA, identifying a new molecular target that could lead to treatment for age-associated diseases.<\/strong><\/figcaption><\/figure><\/div>\n\n\n<h1><a href=\"https:\/\/scitechdaily.com\/scientists-discover-a-gene-that-could-prevent-alzheimers-disease\/\">Scientists Discover a Gene That Could Prevent Alzheimer&#8217;s Disease<\/a><\/h1>\n\n\n\n<p>Researchers at the University of Colorado Anschutz Medical Campus find that overexpression of a gene linked to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer\u2019s disease (AD), despite the presence of amyloid beta (Abeta).<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"576\" src=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05150046\/CRISPR-Cas9--1024x576.jpg\" alt=\"\" class=\"wp-image-10078\" srcset=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05150046\/CRISPR-Cas9--1024x576.jpg 1024w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05150046\/CRISPR-Cas9--300x169.jpg 300w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05150046\/CRISPR-Cas9--768x432.jpg 768w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05150046\/CRISPR-Cas9--1536x864.jpg 1536w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05150046\/CRISPR-Cas9--2048x1152.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h1><a href=\"https:\/\/www.news-medical.net\/news\/20221124\/New-CRISPR-based-tool-can-snip-out-faulty-genes-and-replace-them-with-new-ones.aspx\">New CRISPR-based tool &#8220;PASTE&#8221; can snip out faulty genes and replace them with new ones<\/a><\/h1>\n\n\n\n<p>Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"767\" src=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152851\/national-cancer-institute-W2OVh2w2Kpo-unsplash-1024x767.jpg\" alt=\"\" class=\"wp-image-10096\" srcset=\"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152851\/national-cancer-institute-W2OVh2w2Kpo-unsplash-1024x767.jpg 1024w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152851\/national-cancer-institute-W2OVh2w2Kpo-unsplash-300x225.jpg 300w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152851\/national-cancer-institute-W2OVh2w2Kpo-unsplash-768x575.jpg 768w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152851\/national-cancer-institute-W2OVh2w2Kpo-unsplash-1536x1151.jpg 1536w, https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152851\/national-cancer-institute-W2OVh2w2Kpo-unsplash-2048x1535.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h1><a href=\"https:\/\/newsazi.com\/car-t-cell-therapy-reaches-beyond-cancer\/\">New CAR-T Cell Therapy Reverses Auto-Immune Disease<\/a><\/h1>\n\n\n\n<p>CAR T cells have shown promise in fighting blood cancers, and now there is evidence that they may also be effective in treating autoimmune diseases such as lupus. In a small study, all patients went into remission after receiving CAR T therapy and were able to stop taking their lupus drugs within three months.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists at the University of Cologne have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA). Using a mouse model in which mtDNA mutations lead to impaired muscle regeneration, the scientists were able to demonstrate that selectively mutated mtDNA can be removed by stimulating the activity of the autophagy mechanism with rapamycin. New AI blood [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":10092,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[{"id":40,"name":"Anti-Aging","slug":"longevity","link":"https:\/\/kyla.com\/p\/blog\/category\/longevity\/"}],"tags":[],"featured_image_url":"https:\/\/s3.us-east-1.amazonaws.com\/kyla.com-wordpress\/p\/wp-content\/uploads\/2022\/12\/05152228\/t-cell-immune-system-electron-micrograph-image.jpeg","_links":{"self":[{"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/posts\/10071"}],"collection":[{"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/comments?post=10071"}],"version-history":[{"count":3,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/posts\/10071\/revisions"}],"predecessor-version":[{"id":17678,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/posts\/10071\/revisions\/17678"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/media\/10092"}],"wp:attachment":[{"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/media?parent=10071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/categories?post=10071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kyla.com\/p\/wp-json\/wp\/v2\/tags?post=10071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}